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Historic Debate: Ben Franklin, Smallpox, and Early Vaccine Risks Dr. McCullough traced how vaccine ideology began in 1721 Boston. Cotton Mather and Dr. Boylston promoted “variolation” — taking pus from one child with smallpox to infect another. At first mocked, even by Ben Franklin, the practice gained traction after Franklin’s own son died of smallpox. From the very start, vaccines carried confusion, risk, and misplaced faith. Some children died immediately after variolation, yet leaders presse
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How Onesimus, a Slave in Colonial Boston, Helped Stop a Smallpox Epidemic
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