The FDA has begun soliciting feedback to inform the next version of the Prescription Drug User Fee Act. User fees remain ...

A man from rural India presented with redness and blurry vision in one eye. Examination was notable for panuveitis and a live worm in the posterior segment; the worm was removed in a pars plana vit ...

The author describes the scientific foundations of a clinical trial of a first-in-class small-molecule estrogen receptor degrader to treat patients with metastatic breast cancer.

The rising tide of chronic kidney disease among patients with type 2 diabetes continues to challenge clinicians and health systems worldwide.1 Advances have been made in the management of chronic k ...

Audio Interview from the New England Journal of Medicine — Interview with Tom Frieden on the role of the CDC and current threats to the U.S. public health infrastructure.

The former members of the Advisory Committee on Immunization Practices consider paths forward for U.S. vaccine policy in the wake of their dismissal by the Secretary of Health and Human Services in ...

To prevent the spread of inaccurate information, academic and health care institutions will need to equip scientists and clinicians to engage effectively on nontraditional media platforms.

Explore this issue of The New England Journal of Medicine (Vol. 393 No. 5).

The need to suppress a patient’s immune system after the transplantation of allogeneic cells is associated with wide-ranging side effects. We report the outcomes of transplantation of ...

How much is enough in the treatment of newly diagnosed multiple myeloma? As clinicians, we want to provide efficacious treatments for our patients to avoid undertreating them. However, we also want ...

Although xenon may have neuroprotective effects, there is no strong evidence that it aids in short-term, high-altitude performance. Success is more likely a result of acclimatization, oxygen suppor ...

Understanding today’s corporatization of U.S. health care requires seeing it from a historical perspective, as a process that began with a change in the business model of care delivery in the 1920s.