Journal of Nuclear Medicine

High-Intensity Focused Ultrasound in Prostate Cancer: Can PSMA PET Improve Focal Therapy Outcomes?

High-intensity focused ultrasound (HIFU) is an increasingly used, locally ablative therapy option in localized prostate cancer (PCa). Multiparametric MRI (mpMRI) is currently used for tumor ...
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A Computational Multinephron Model for Small-Scale Preclinical Renal Dosimetry in Radiopharmaceutical Therapy

Journal of Nuclear Medicine October 2025, jnumed.125.270151; DOI: https://doi.org/10.2967/jnumed.125.270151 ...
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Extravasation of Therapeutic Radiopharmaceuticals: A Systematic Review and Management Proposal

Journal of Nuclear Medicine October 2025, jnumed.125.270215; DOI: https://doi.org/10.2967/jnumed.125.270215 ...
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Lymphoma Therapy Response Assessment with Low-Dose

Journal of Nuclear Medicine August 2025, jnumed.124.268841; DOI: https://doi.org/10.2967/jnumed.124.268841 ...
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CD24 as a Novel Radiopharmaceutical Target for Hepatocellular Carcinoma

Journal of Nuclear Medicine July 2025, jnumed.125.270167; DOI: https://doi.org/10.2967/jnumed.125.270167 ...
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225 Ac α-Pretargeted Radioimmunotherapy of Human Epidermal Growth Factor Receptor 2–Expressing Breast Cancer

Radioimmunotherapy using 225Ac, a highly cytotoxic α-particle emitter, has potential for treating advanced breast cancer, especially human epidermal growth factor receptor 2 (HER2)–positive cases. We ...
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GPC3-targeted immunoPET allows for early detection of HCC: a pilot clinical study

Journal of Nuclear Medicine June 2025, 66 (supplement 1) 252173; ...
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Approaches to Imaging Immune Activation Using PET

This review explores the role of PET in imaging immune activation, particularly in oncology. 18 F-FDG is widely used for assessing treatment response to immunotherapies and can demonstrate unique ...
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Designed Ankyrin Repeat Protein–Mediated Peptide Nucleic Acid–Based Pretargeting: A Proof-of-Principle Study

Journal of Nuclear Medicine May 2025, jnumed.125.269533; DOI: https://doi.org/10.2967/jnumed.125.269533 ...
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A Phase I/II Study of

Journal of Nuclear Medicine April 2025, jnumed.124.269064; DOI: https://doi.org/10.2967/jnumed.124.269064 ...
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Prevalence of Persistent Cardiovascular and Pulmonary Abnormalities on PET/MRI and DECT Imaging in Long COVID Patients

Journal of Nuclear Medicine April 2025, jnumed.124.268980; DOI: https://doi.org/10.2967/jnumed.124.268980 ...
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225 Ac/ 89 Zr-Labeled N4MU01 Radioimmunoconjugates as Theranostics Against Nectin-4–Positive Triple-Negative Breast Cancer

Nectin-4 is an overexpressed biomarker in 60%–70% of triple-negative breast cancer (TNBC) cases and an ideal target for radiotherapy and PET imaging. In this study, theranostic radioimmunoconjugates ...