The San Francisco 49ers are bracing for a challenging matchup against the Buffalo Bills this Sunday, not only due to the ...

Under head coach Kyle Shanahan, the San Francisco 49ers have spent years falling just inches short of the franchise’s sixth ...

The 49ers have dealt with injuries to key players all season. Brandon Aiyuk injured his knee, Brock Purdy missed last week's ...

This week, Nick Bosa was asked about the 49ers' upcoming opponent, Bills quarterback Josh Allen. Here's what Bosa said. Q: ...

The San Francisco 49ers face a critical clash against the Buffalo Bills this Sunday, and defensive end Leonard Floyd is ...

The Lions kicked off the Thanksgiving slate with a close win over the Bears, who let another tight game slip away in the ...

Kyle Shanahan pushed back against the negativity and “unrealistic” expectations regarding Christian McCaffrey’s production in ...

Buffalo Bills linebacker Matt Milano has missed the first 11 games of the 2024 season with a bicep injury. Will he return ...

Aaron Rodgers and the New York Jets have lost seven of their last eight games and now will host the Seattle Seahawks for a ...

Brock Purdy threw one short pass in the open portion of practice for the San Francisco 49ers as he remains slowed by an ...

San Francisco 49ers wide receiver Deebo Samuel has had quite a turbulent season, and he’s starting to feel the heat because ...

The Buffalo Bills will play the San Francisco 49ers at home at Highmark Stadium on "Sunday Night Football" in Week 13. The ...