HER2-positive gastric cancer accounts for a substantial proportion of advanced cases and has long been treated with HER2-targeted therapies. While trastuzumab deruxtecan has shown superior activity ...

Treatment with molecular shipping containers loaded with a signaling molecule reduced the severity of pulmonary hypertension in a rat model.

NSCLC remains the leading cause of cancer-related mortality worldwide, with EGFR mutations being a critical driver in approximately 10-15% of lung adenocarcinomas in Western populations, and up to 40% ...

In a new study published in the journal Nature Genetics, Haolong Li, PhD, a researcher at Fred Hutch Cancer Center, and colleagues developed a way to monitor androgen receptor levels inside living ...

The convergence of CNS and oncology research amplifies the significance of Oncotelic’s recent intellectual property updates for OT-101. Developed in collaboration with Sapu Bioscience, the expanded ...

Stenoparib is being evaluated in combination with temozolomide clinical benefit in relapsed Small Cell Lung CancerTrial is fully funded by ...

Cancer in women presents distinct biological and clinical challenges that extend beyond tumor control alone. Sex specific differences in metabolism, ...

As is often the case with cancer treatments, many patients are able to benefit from therapy for a time. Tumor activity ...

Biotech dealmaking is increasingly defined by a clear strategic shift: Pharmaceutical companies are prioritizing de-risked, late-stage assets with human clinical validation rather than speculative ...

Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs, MDSCs, and Tregs-orchestrate a tumor-permissive microenvironment.

A newly discovered link between pancreatic cancer and neural signaling reveals a promising drug target that slows tumor ...

Hyperactive signaling pathways of some aggressive blood cancer cells can be tamped down by a previously unrecognized protein complex, ensuring the cancer's survival. If one component of the complex is ...