Researchers discover L1td1 maintains stem cell pluripotency by degrading totipotency-associated RNAs
A new study has found that L1td1, a protein evolutionarily co-opted from the Long interspersed nuclear element 1 (LINE1) ...
MicroRNAs are central regulators of DLBCL biology and show strong potential as minimally invasive biomarkers to improve ...
New study reveals how cytoplasmic and nuclear functions of USP30-AS1 converge to promote tumor growth Breast cancer progression is increasingly ...
A new study has found that L1td1, a protein evolutionarily co-opted from the Long interspersed nuclear element 1 (LINE1) ...
GlobalData on MSN
RNA-targeting small molecules: a new frontier of drug discovery
With big pharma signalling interest in novel RNA-targeted approaches, the term “druggable” is being redefined as technology advances.
Grafting is a widely used agricultural technique, but the slow and unreliable healing of graft unions often limits its efficiency.
HRN001 is a potent and specific antisense oligonucleotide designed to drive controlled upregulation of FAN1, a genetically validated ...
This study proposes a cross-species transcriptomic framework to predict vaccine reactogenicity, with implications for preclinical vaccine safety assessment. The findings show that mouse muscle ...
From molecular chaperones to mitochondrial failure, discover how heat reshapes the human transcriptome and drives the biological cascade that links rising temperatures to organ injury and public ...
Researchers uncover a redox-regulated mechanism that determines whether bone fractures heal or progress to nonunion ...
Conditional genetics and single-embryo RNA-seq show that SETDB1 extinguishes the transient, retroelement-driven transcriptional programs of the totipotent two-cell state to facilitate the exit from ...
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