Under head coach Kyle Shanahan, the San Francisco 49ers have spent years falling just inches short of the franchise’s sixth ...

Watch out for the tables on "Sunday Night Football." The nightcap of Sunday's action will be in northern New York with the ...

We thought San Francisco was poised for a massive second-half run after the Week 9 bye with Christian McCaffrey back, but the ...

San Francisco 49ers linebacker Fred Warner says he has been playing through a fractured bone in his ankle since Week 4.

The 2024 49ers simply aren't good. That's why they've fallen to 18th in NFL.com's Week 13 power rankings. This is the 49ers' ...

The 49ers have dealt with injuries to key players all season. Brandon Aiyuk injured his knee, Brock Purdy missed last week's ...

The Buffalo Bills are fresh off of their bye week heading into a Sunday Night Football matchup with the San Francisco 49ers, ...

Just when it looked like the defending NFC champions were getting their act together after a slow start, there go the 49ers.

Before locking in any Packers vs. 49ers picks, you'll want to see the NFL predictions and betting advice from the proven ...

Chicago Bears quarterback Caleb Williams set an NFL rookie record in a Thanksgiving Day loss to the Detroit Lions on Thursday ...

NFL Week 13 odds, picks, predictions, TV and streaming information for Sunday Night Football game between the San Francisco ...