Objective To investigate a possible association between fever admissions and 4 component Meningococcal B (4CMenB). Design 4CMenB is given at 8 and 16 weeks in the first year of life. Self-controlled ...

Objectives Describe clinical characteristics, treatment and outcomes of children treated for life-threatening pertussis in paediatric intensive care units during the 2023–2024 outbreak in Great ...

Importance The role of intravenous aminophylline in acute asthma in childhood is unclear. Objectives To assess the safety and efficacy of intravenous aminophylline for asthma in children. Methods From ...

Importance The role of intravenous short-acting beta-2 agonist (SABA) in acute asthma in childhood is unclear. Objectives To assess the safety and efficacy of intravenous SABA versus placebo for acute ...

Background Women lacking social support during pregnancy often have worse mental health, but we know little about the influence of social support on child development, or the impact for migrant women.

We encounter, occasionally, parents who are incapable of making medical decisions on behalf of their incompetent or incapacitated children. When the incapable parent is themselves a child; measures ...

Background Gender identity services for children and young people are currently being reorganised in England and Wales. Provision is required to negotiate clinical uncertainty and a public debate that ...

Background Over the last few years, there has been increasing attention to the involvement of the central nervous system in Duchenne muscular dystrophy (DMD). The aim of this study was to assess the ...

Background The gold standard of paediatric obstructive sleep apnoea syndrome (OSAS) diagnosis is overnight polysomnography (PSG). Validated screening methods for paediatric OSAS are limited.

Nirsevimab, a long-acting monoclonal antibody, was introduced last season (2023–2024) in some countries with the aim of reducing the burden of disease caused by respiratory syncytial virus (RSV) in ...

Objective To evaluate the efficacy differentials among corticosteroid regimens by type, dosage and duration, we conducted a systematic review and network meta-analysis of randomised controlled trials ...

Objective To validate a short parent-reported outcome (PRO) questionnaire in young boys with conditions affecting sex development (PRO-CSD). Design Consecutive sample cross-sectional study. Setting A ...