San Francisco 49ers running back Christian McCaffrey is three games into his return from injury. The two-time first-team ...

The Buffalo Bills will play the San Francisco 49ers at home at Highmark Stadium on "Sunday Night Football" in Week 13. The ...

See who's in and who's out for the Week 13 matchup between the Buffalo Bills and San Francisco 49ers on December 1, 2024.

The 49ers have revealed their latest injury report from Wednesday’s practice before their Sunday Night Football tilt against ...

The AFC East-leading Buffalo Bills return from their bye week to host the inconsistent San Francisco 49ers on Sunday night.

San Francisco 49ers quarterback Brock Purdy was limited with the right shoulder injury that sidelined him last week and there ...

San Francisco 49ers linebacker Fred Warner says he has been playing through a fractured bone in his ankle since Week 4.

San Francisco 49ers star linebacker Fred Warner revealed that he has been playing through a broken bone in his ankle since ...

The banged-up San Francisco 49ers received some positive news on Wednesday. Per ESPN's Nick Wagoner, 49ers head coach Kyle ...

Deebo Samuel probably is the most disappointing player on the most disappointing team in the NFL through 12 weeks. Despite ...

Weather looks set to play a role in the Buffalo Bills' Week 13 matchup with the San Francisco 49ers.

Christian McCaffrey and the 49ers travel to Buffalo to take on Josh Allen and the Bills for Sunday Night Football. Live ...