Abstract: This letter presents an enhanced Trust Region Method (TRM) for Sequential Linear Programming (SLP) designed to improve the initial feasible solution to a constrained nonlinear programming ...

Bezafibrate improves cholestatic biomarkers. In addition, on-treatment ALP levels are significantly associated with clinical outcomes among those with PBC. Off-label use of bezafibrate is associated ...

An HR advisor with a background in recruitment and HRIS functions, with a passion for video games and writing. Oliver grew up playing Call of Duty with his siblings and has garnered 1000s of hours ...

Salivary antimitochondrial antibodies-M2 and pyruvate dehydrogenase complex E2 autoantibodies show high specificity for noninvasive diagnosis of primary biliary cholangitis. Certain salivary ...

Some patients with PBC reported positive engagement with their general practitioner, while others reported gaps in knowledge and support. Primary care plays a complex role in the management of primary ...