Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.
Neuroscientists discover that Rett syndrome mutations cause a leaky brain via overexpressed miRNA-126-3p, pointing to a new therapeutic target for vascular repair.
Since scientists first discovered that human immune cells could be modified to become cancer-fighting agents, they've been trying to engineer a cell that's effective against solid tumors, which ...
A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...
Immunexpress, a molecular diagnostics company focused on improving outcomes for patients with suspected sepsis, today ...
Vector-borne diseases (VBDs) represent a critical challenge in infectious disease control due to their complex transmission dynamics, diverse vector ...
On Thursday, Feb. 19, Ali May, an assistant professor at the Icahn School of Medicine at Mount Sinai presented her research on the various ways tissue resident macrophages shape embryonic salivary ...
New findings reveal how the gene HNRNPU coordinates several fundamental molecular processes during the earliest stages of ...
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The life cycle of a protein
A protein’s life is anything but simple. Discover how transcription, translation, folding, modification, and degradation work together to preserve proteome integrity.
This article takes a deep dive into the history of proteomics from the conception of the term “proteome” up to modern-day advances in bioinformatics and single-cell protein analysis.
New techniques to detect Y chromosome genes show frequent loss of the Y in tissues of older men. The increase with age is clear: 40% of 60-year-old men show loss of Y, but 57% of 90-year-olds.
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