Relapsing after quitting cocaine is not simply a matter of willpower — it reflects physical changes in the brain, according to new research. Scientists have found that repeated cocaine use reshapes ...

A non-intoxicating compound in cannabis could offer a breakthrough treatment for alcohol use disorder. New research shows CBD ...

A mouse study highlights the role of acetylcholine in behavioral flexibility, offering new insight into the brain mechanisms involved in addiction and obsessive compulsive disorder.

Researchers have used mouse models to study how cocaine addiction alters the brain, illuminating why relapse is common as ...

Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.

Most of the genetic risk for developing a substance use disorder comes from genes that broadly affect how our brains process ...

With millions struggling with cocaine use, the lack of medical treatments remains a public health crisis. A recent study at Michigan State University identified a specific protein that acts as a ...

GLP-1 medications like semaglutide (Ozempic) may offer unexpected mental health benefits alongside weight loss. A large study found major drops in depression, anxiety, and psychiatric-related hospital ...

We have long been told a simple story about reward: Dopamine is the "wanting" molecule that drives us toward goals, and ...

New research suggests the weight-loss medications could be powerful tools in tackling substance use disorders.