This week, Nick Bosa was asked about the 49ers' upcoming opponent, Bills quarterback Josh Allen. Here's what Bosa said. Q: ...

Buffalo Bills linebacker Matt Milano has missed the first 11 games of the 2024 season with a bicep injury. Will he return ...

The Buffalo Bills will play the San Francisco 49ers at home at Highmark Stadium on "Sunday Night Football" in Week 13. The ...

Kyle Shanahan pushed back against the negativity and “unrealistic” expectations regarding Christian McCaffrey’s production in ...

See who's in and who's out for the Week 13 matchup between the Buffalo Bills and San Francisco 49ers on December 1, 2024.

Watch out for the tables on "Sunday Night Football." The nightcap of Sunday's action will be in northern New York with the ...

Christian McCaffrey is deadly serious about his 9-to-5 job — head coach Kyle Shanahan calls him “a psycho in the best way ...

Brock Purdy threw one short pass in the open portion of practice for the San Francisco 49ers as he remains slowed by an ...

Under head coach Kyle Shanahan, the San Francisco 49ers have spent years falling just inches short of the franchise’s sixth ...

Matt Maiocco shares the latest practice report for the San Francisco 49ers and Buffalo Bills ahead of their Week 13 game on ...

The 49ers have dealt with injuries to key players all season. Brandon Aiyuk injured his knee, Brock Purdy missed last week's ...

San Francisco 49ers star Deebo Samuel had a blunt reaction when asked about his low numbers to begin this season.