The Bills return from the bye for a primetime showdown with the 49ers in NFL Week 13 on Sunday, Dec. 1 at Highmark Stadium.

Four NFL games on Thanksgiving and Black Friday kicked off Week 13 action, and the full schedule continues on Sunday, Dec. 1, ...

The National Weather Service has extended its "lake effect snow warning" in Buffalo through Monday at 7 p.m. ET, with ...

There are no teams on bye around the NFL in Week 13, which means we'll be treated to a packed slate of Sunday games even ...

The Buffalo Bills will look to lock up a playoff spot in their Week 13 showdown with the San Francisco 49ers. Here are five ...

We thought San Francisco was poised for a massive second-half run after the Week 9 bye with Christian McCaffrey back, but the ...

San Francisco has been up and down all season, but the Super Bowl hangover appears to be happening after the 49ers got ...

NFL Week 13 odds, picks, predictions, TV and streaming information for Sunday Night Football game between the San Francisco ...

Take a look at the 16 games on the Week 13 NFL schedule this week, starting with three games on Thanksgiving ( Chicago Bears ...

The game can be streamed live on Peacock, as well as through the NBC Sports app and NBCSports.com (with a cable or satellite ...

The 49ers have dealt with injuries to key players all season. Brandon Aiyuk injured his knee, Brock Purdy missed last week's ...

San Francisco 49ers linebacker Fred Warner says he has been playing through a fractured bone in his ankle since Week 4.