There are always a few things to learn from the San Francisco 49ers in every win or defeat. That includes an expected 41-22 ...

Wilson caught 15 passes for 185 yards, coming close to matching in one game his entire season's production previously.

Arizona had the passing game working, but it didn't matter in a 41-22 loss to San Francisco at State Farm Stadium in Glendale ...

In the Arizona Cardinals ' 41-22 loss to the San Francisco 49ers on Sunday, 20 players participated in at least one of the 79 ...

With the defense and special teams coming up with big plays, the 49ers dominate Cardinals in Brock Purdy’s return.

Brock Purdy returned from a six-game absence to throw three touchdowns as the 49ers (7-4) romped to a 41-22 win over the host ...

Once again, the Arizona Cardinals found themselves on the wrong end of a one-sided score against a divisional opponent.

A former NFL star accused the Arizona Cardinals of point-shaving against the 49ers on Sunday after San Francisco cruised to a ...

Kyle Shanahan said Brock Purdy "checked out all right" after his first game back. Linebacker Tatum Bethune, however, didn't ...

San Francisco 49ers tight end George Kittle (85) catches a touchdown pass in front of Arizona Cardinals linebacker Akeem ...

Former Pro Bowl RB LeSean McCoy believes the Arizona Cardinals point shaved in their Week 11 loss to the San Francisco 49ers.

Brock Purdy came through the Arizona game healthy, but kicker Eddy Piñeiro and linebacker Tatum Bethune did not.