CAPE GIRARDEAU, Mo. (KFVS) - Two people had to be treated for smoke inhalation after a fire heavily damaged two homes in Cape ...

Santa and Mrs. Claus made a pit stop in Sikeston to bring hundreds of toys, smiles, and holiday cheer to families.

MISSISSIPPI COUNTY, Mo. (KFVS) - The Missouri Highway Patrol says a single-vehicle crash is blocking U.S. 60/62 in ...

GREENE COUNTY, Mo. (KY3) -A small plane made an off-field landing on a highway in southwest Missouri, officials said Saturday ...

WASHINGTON (AP) — U.S. forces on Saturday stopped a vessel off the coast of Venezuela for the second time in less than two ...

Meteorologist Madeline Parker says you can expect clear and sunny skies throughout the day, with temperatures starting off ...

City officials joined the Missouri Department of Transportation for a ribbon cutting ceremony to celebrate a finished walkway ...

FRANKLIN COUNTY, Ill. (KFVS) - First responders are at the scene of a crash on Interstate 57 in southern Illinois. According to the Franklin County Office of Emergency Management, the crash is in the ...

There will be a visit from Santa, music and singing, a petting zoo and hot chocolate and cookies for the community to enjoy.

St. Francis CARE in Murphysboro is inviting people to make the season brighter for pets spending Christmas in the shelter.

Julihanna Felton, a 3rd grader in Carbondale, is on a mission to keep members of her community warm this Christmas season.

St. Francis Hospital sent a WARN letter to the Missouri Department of Higher Education and Workforce Development regarding ...