This study presents valuable findings from a spatiotemporal analysis of arbovirus case notification data from 2013 to 2020 in Brazil, reporting associations between covariates representing potential ...

This study offers a valuable advance for neuroscience by extending a visualization tool that enables intuitive assessment of how dendritic and synaptic currents shape the output of neurons. The ...

The articles in this focus issue discuss progress towards a more complete understanding of memory in the innate immune system, and efforts to exploit "trained immunity" for the development of new ...

Our latest Focus Issue looks at what we’ve learnt over the past decade and what’s next for the field of trained immunity.

Loss of the glutamate transporters EAAT5b and EAAT7 disrupts wavelength-specific visual processing and UV-dependent prey detection in zebrafish, revealing their key roles in modulating light ...

This study provides fundamental information on how Arg-II participates in cardiac aging. The phenotypic data provide convincing evidence of non-cell-autonomous contributions to aging-related ...

The first biologically inspired computer model, comprising multiple multisensory correlation detectors, can integrate spatially and temporally congruent audiovisual information in a similar way to ...

The role of megafaunal exploitation in early human evolution remains debated. Occasional use of large carcasses by early hominins has been considered by some as opportunistic, possibly a fallback ...

The pathogenic bacteria Shigella avoids detection inside hosts cells by degrading RNF213, the protein responsible for sensing the presence of intracellular pathogens.

This study presents valuable findings on the role of KLF6 in in vitro endothelial cells exposed to altered (high or low) shear stress with a customized microfluidic device to investigate mechanisms of ...

Muscle-derived branched-chain amino acids support thermogenesis in brown adipose tissue, thereby helping maintain body temperature during impaired muscle function or physiological stress.

This important study examines the potential role of ARHGAP36 transcriptional regulation by FOXC1 in controlling sonic hedgehog signaling in human neuroblastoma. While there are many solid findings ...