In a study published in the Clinical and Translational Medicine, a Nanjing University research group evaluated the on- and off-target effects of self-assembled siRNA delivery system. RNA interference ...

In liver, lipid nanoparticles (LNPs) were first used to deliver patisiran, currently the only siRNA drug on the market that uses this technology platform. The animal POC studies of LNP-mediated siRNA ...

New RNA-based active agents reliably protect plants against the Cucumber mosaic virus (CMV), the most common virus in agriculture and horticulture. They were developed by researchers at the Martin ...

The higher-order architecture observed in biological systems, like viruses, is very effective in nucleic acid transport. The replications of this system has been attempted with both synthetic and ...