Scientists at deCODE genetics, a subsidiary of Amgen and their collaborators from Iceland, Denmark and USA published a study today in Nature Structural and Molecular Biology titled “Variant in the ...

A cartoon of paired homologous chromosomes (blue) with the synaptonemal complex (SC, green) assembled between them. Below, from top to bottom, are cartoons depicting the localization of proteins in a ...

Enter the synaptonemal complex (SC), a zipper-like protein structure that lines up and anchors the two parental chromosomes together, end-to-end, to facilitate successful genetic exchanges. Failure to ...

Scientists at deCODE genetics, a subsidiary of Amgen and their collaborators from Iceland, Denmark and USA published a study today in Nature Structural and Molecular Biology titled "Variant in the ...

Every new life begins after a genetic shuffle. When organisms make eggs or sperm, maternal and paternal chromosomes pair up and swap pieces of DNA in a process called crossing over. This exchange is ...

Scientists have discovered an association between a variant in the synaptonemal complex protein, SYCE2, and pregnancy loss through the effects of recombination. An international collaboration led by ...

Meiotic recombination is a specialised process in which programmed DNA double-strand breaks initiate the exchange of genetic material between homologous chromosomes. This exchange forms crossovers ...

Biologists developed a method for illuminating the intricate interactions of the synaptonemal complex in the nematode C. elegans. The authors identified a trio of protein segments that guide ...