A game-changining achievement in genome science has identified over 140,000 distinct DNA loops in our cells, providing chromosome fold resolution that is among the best ever created. In this ongoing ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

CpG density and epigenetic modification state modulate DNA mechanics, altering its intrinsic compatibility with nucleosome formation.

If stretched out, human DNA would be about 2 meters long. For this long strand to fit inside the cell nucleus, which is about ...

In a recent study published in PNAS, researchers introduced the Genomic Pre-trained Network (GPN), a multispecies model developed to learn genome-wide variant effects by self-supervised pretraining on ...

James D. Watson, whose role as co-discoverer of the structure of the DNA molecule in 1953 made him one of the key figures in the rise of molecular biology as well as the obvious choice to be first ...

“The laws of inheritance are quite unknown,” Charles Darwin acknowledged in 1859. The discovery of DNA’s shape altered how we conceived of life itself. The X-ray crystallography by Rosalind Franklin ...

James Dewey Watson, whose co-discovery of the twisted-ladder structure of DNA in 1953 helped launch a revolution in biology and medicine, died Thursday at age 97. He died in hospice care after a brief ...

James Watson, a renowned molecular biologist and one of the Nobel Prize winners for discovering the structure of DNA, died Thursday after a brief illness, according to a statement from his former ...