Spatial ribonucleic acid (RNA) transcriptomics measures gene expression while preserving each molecule’s coordinates in intact tissue, tying transcripts to histology and local microenvironments.

Challenges and Prospects. Challenges and prospects faced by spatial transcriptomics itself and its application to the musculoskeletal system. AI Artificial intelligence, FFPE Formalin fixed and ...

Although numerous spatial transcriptomics analyses exist for evaluating RNA localization, these methods face several limitations. Cell fractionation techniques, such as density gradient centrifugation ...

Spatial biology is reshaping how researchers study cancer by revealing the architecture and complexity of tumors in extraordinary detail. Through techniques that combine protein- and gene-level ...

Left: Imaging of lamin A/C structures in a physically expanded nucleus from an individual with progeria. Right: Same, but with 3D genomic reads overlaid in their original spatial locations, colored by ...

Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes, the DNA blueprint for these cells is essentially the same. Where do those differences come ...

Researchers at University Medical Center Utrecht have uncovered a previously underappreciated mechanism that helps immune ...

Spatial omics is transforming how researchers understand tissue biology, revealing the complex interplay between cells in health and disease. While RNA expression studies provide important molecular ...