Pancreatic cancer, also known as pancreatic ductal adenocarcinoma, is one of the most aggressive types of cancer. Despite ...

With this growing body of evidence, Artelo continues to expand its leadership in the FABP inhibitor space. The Company maintains a portfolio of selective, dual, and pan inhibitors targeting FABP3, ...

These particles don't just sit harmlessly in the body; they trigger chronic inflammation, oxidative stress, and DNA damage.

By stimulating cancer cells to produce a molecule that activates a signaling pathway in nearby immune cells, MIT researchers ...

Researchers can use messenger RNA to trigger the immune system to attack tumors. By stimulating cancer cells to produce a ...

Immune system activation and activity is regulated through stimulatory or inhibitory ligand-receptor interactions collectively termed immune checkpoints. 1 Stimulatory interactions give the immune ...

Tumors were eradicated in 30% of mice receiving cGAS LNPs injected into the tumor, in combination with immune checkpoint blockade.

Panel A summarizes the conventional model of how oncogenic RAS guanosine triphosphatases (i.e., Kirsten rat sarcoma viral oncogene homologue [KRAS], neuroblastoma RAS viral oncogene homologue [NRAS], ...

A comprehensive review in Current Molecular Pharmacology reveals how TCF/LEF proteins control Wnt signaling through dynamic enhanceosome assembly, post-translational modifications, and isoform ...