Achieving high-resolution, label-free imaging deep within highly scattering biological tissues remains a major challenge in optical microscopy 1,2, critical for understanding fundamental biological ...

Large-field nanoscale fluorescence imaging is invaluable for many applications, such as imaging subcellular structures, visualizing protein interactions, and high-resolution tissue imaging.

Figure 1 (a) Structure of the mesoscopic objective, (b) Aberration distribution of the mesoscopic objective, (c) Wide-field imaging system built with the mesoscopic objective, (d) Laser point-scanning ...