An international collaboration steered by David Cortez, Richard N. Armstrong, Ph.D. Chair for Innovation in Biochemistry, explored how cells tolerate DNA damage and genome instability—and they arrived ...
The complete and accurate replication of the genome is essential to maintain genome integrity. Replication forks face many obstacles that can result in replication fork stalling or replication fork ...
The dire consequences of a poor response to replication stress are clinically apparent in genetically inherited premature aging disorders 3. A common feature of these diseases is chromosomal ...
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