A new radioimmunotherapy approach has been shown to successfully eliminate cancer stem cells (CSCs) in preclinical models of ovarian cancer, outperforming the current gold standard. This research, ...
Scientists have piggybacked antibodies onto radioactive payloads to deliver doses of radiation that selectively target and destroy microbial and HIV-infected cells. The experimental treatment -- ...
Radioimmunotherapy might be useful as an initial and standalone treatment for follicular non-Hodgkin's lymphoma, according to a phase 2 study. The study, by Christian Scholz, MD, and colleagues from ...
A new pretargeted radioimmunotherapy (PRIT) technique has been shown to be safe and effective in eradicating tumors from a preclinical colorectal cancer model. The multi-step theranostic approach ...
Results from a Phase 1 clinical trial for a cancer therapy show the potential to kill colorectal tumors with less destruction of healthy tissue. Further research could lead to the use of this ...
VANCOUVER, British Columbia — In patients with refractory or relapsed aggressive lymphoma, immunoradiation combined with high-dose chemotherapy is associated with better progression-free and overall ...
A new radioimmunotherapy has proven effective in reversing resistance to the most commonly used lymphoma drug, rituximab, according to research published in the October issue of The Journal of Nuclear ...
Prognostic Significance of Partial Tandem Duplications of the MLL Gene in Adult Patients 16 to 60 Years Old With Acute Myeloid Leukemia and Normal Cytogenetics: A Study of the Acute Myeloid Leukemia ...
A major advance in cancer therapy—high dose radioimmunotherapy—resulted in long-term remission for persons with mantle cell lymphoma. This often-fatal form of Non-Hodgkin’s Lymphoma (NHL) has a mean ...
Monoclonal antibody–based therapeutics for cancer patients has recently proven to be highly successful. 1 A number of these new treatments have been based on the ability of monoclonal antibodies to ...
Radioimmunotherapy, targeting the CD20 antigen, in B-cell lymphoma has clearly demonstrated efficacy and tolerability over the preceding 15 years. As a result, two products are available with Food and ...
Multiple myeloma (MM) is characterized by the monoclonal expansion of malignant plasma cells in the bone marrow (BM) and the production of monoclonal protein (M-protein). With the implementation of ...
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