A new method developed at Baylor College of Medicine and collaborating institutions allows researchers to better understand how RNA works. The method is a powerful strategy for identifying intricate ...

This manuscript has convincing data that provides a high-resolution structure of the Egl-RNA complex. The findings are important to understand the formation, stability, and interactions of this ...

The field of neurodegenerative disease research has increasingly focused on the roles of RNA-binding proteins in the pathogenesis of amyotrophic lateral ...

A new biochemical method identifies RNA 3D structures and protein binding sites in cells. It reveals how RNA folding drives ...

Researchers led by Davide Incarnato at the University of Groningen have demonstrated that the FDA-approved cancer drug mitoxantrone works against RNA not simply by attaching to it, but by forcing it ...

Researchers at the University of Toronto have shown that an important class of DNA-binding factors can also bind to RNA, regulating gene expression through various mechanisms. The study significantly ...

Our immune systems are remarkably adept at sounding the alarm when something goes wrong—sometimes even to the point of overreacting. But what happens when a notorious oncoprotein like MYC learns to ...

Inosine is a nucleoside that occurs naturally in transfer RNAs (tRNAs) and is essential for proper RNA translation. It is commonly found at the wobble position of anticodons, allowing for greater ...

A new method developed at Baylor College of Medicine and collaborating institutions allows researchers to better understand how RNA works. The method, published in Molecular Cell, is a powerful ...