On Wednesday, the Nobel Committee announced that it had awarded the Nobel Prize in chemistry to researchers who pioneered major breakthroughs in computational chemistry. These include two researchers ...

Computer program MUMBO makes use of rotamer libraries to build amino acids and their preferred orientations at user-specified sites. It then relies on side chain-packing algorithms and an energy ...

Current AI tools for designing macromolecules have been struggling with DNA and RNA structure prediction and design as significantly less experimental training data are available for nucleic acids ...

Deep learning methods have been used to augment existing energy-based physical models in 'do novo' or from-scratch computational protein design, resulting in a 10-fold increase in success rates ...

A protein created by RFdiffusion3, a newly released protein design tool from Nobel laureate David Baker’s lab, interacting with DNA. (UW Institute for Protein Design / Ian C. Haydon Image) David Baker ...

Protein design aims to create customized antibodies for therapies, biosensors for diagnostics, or enzymes for chemical reactions. An international research team has now developed a method for ...

A new study in Nature reports an AI-driven advance in biotechnology with implications for drug development, disease detection, and environmental monitoring. Scientists at the Institute for Protein ...

AI2 Incubator’s Jenny Cronin (left), interviews David Baker, director of the University of Washington’s Institute for Protein Design. (GeekWire Photo / Charlotte Schubert) The Institute for Protein ...

Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...

AI thrives on data but feeding it the right data is harder than it seems. As enterprises scale their AI initiatives, they face the challenge of managing diverse data pipelines, ensuring proximity to ...

Overview of protein engineering strategies. Directed evolution mimics natural selection in the laboratory through iterative rounds of mutagenesis and screening. Rational design uses structural and ...