Osteogenic differentiation of mesenchymal stem cells (MSCs) is orchestrated by a sophisticated network of non‐coding RNAs (ncRNAs), including microRNAs (miRNAs), long non‐coding RNAs (lncRNAs) and ...

RNA interference (RNAi) is a conserved post-transcriptional gene regulatory pathway whereby short non-coding RNAs guide silencing complexes to complementary messenger RNAs, resulting in translational ...

Scripps Research postdoctoral researcher Kaushik Chanda explores the mechanisms by which non-coding transcripts modulate neuronal function and structural integrity during learning and memory loss.

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are linked to many diseases. Until now, the genetic basis ...

A research team has uncovered a previously unknown RNA-based control system that helps tea plants regulate amino acid ...

Long non-coding RNAs (lncRNA) are a type of RNA molecule that do not carry instructions to make proteins. Instead, they influence how other genes are expressed. There are tens of thousands of lncRNAs ...

Northwestern Medicine scientists have discovered that a specific long non-coding RNA activates oncogenic signaling pathways in prostate cancer cells and drives tumor progression, underscoring its ...

Small RNA therapeutics can modulate multiple genes. This ability may counter tumor adaptation and resistance, overcoming the ...

In back-to-back studies published in Nature, researchers from Purdue University and Columbia University report a naturally evolved gene-editing system that can activate genes, offering an advantage ...

CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing attention as a next-generation gene therapy platform due to its precision and reduced side effects. Utilizing this system, ...