Mast cells are pivotal effectors in immune responses, acting as both sentinels and mediators in allergic and inflammatory processes. Their ability to rapidly degranulate and release a myriad of ...

Eosinophils and mast cells are two types of immune cells with critical roles in responding to foreign assaults. When these cells do not function properly, several disease outcomes can develop (e.g.

Barzolvolimab achieved sustained complete responses and improved quality of life in patients with CSU up to 76 weeks post-treatment. The therapy targets mast cells by inhibiting receptor tyrosine ...

Food allergy, or the aggressive immune system reaction following the consumption of a certain food or food ingredient, ...

In early 2020, Wynde Dyer walked into the house that would transform her life. The Central California ranch sat on a cul-de-sac of gated homes and glittering aquamarine pools. It boasted private ...

For many patients with diverse and seemingly unrelated symptoms, obtaining an accurate diagnosis can take years of specialist visits and inconclusive tests. Mast cell activation syndrome, a disorder ...

Food allergy, or the aggressive immune system reaction following the consumption of a certain food or food ingredient, typically involves immunoglobulin E (IgE) antibodies and can be potentially ...

A new approach to treat rosacea and other inflammatory skin conditions could be on the horizon, according to a University of Pittsburgh study published today in Science Translational Medicine. The ...

On Tuesday, Celldex Therapeutics, Inc. (NASDAQ:CLDX) released topline results from its ongoing Phase 2 study of barzolvolimab in eosinophilic esophagitis (EoE), a chronic inflammatory disease of the ...

MCAS patients and taxpayers deserve better. The solutions exist. What’s missing is the political will to treat this like the crisis it already is.