A new study reveals that reactivating the body’s natural cellular cleanup system could help slow or even reverse key ...

In a rare disease called mucolipidosis type II, people's hearts and abdomens swell, and their bones grow malformed. A lysosomal storage disorder, mucolipidosis type II causes edema of the internal ...

Over the last few decades, neurodegenerative diseases became one of the top 10 global causes of death. Researchers worldwide are making a strong effort to understand neurodegenerative diseases ...

A team of researchers led by Osaka University unravel a tangle of pathways involving calcium, lipids, and the degradation of damaged lysosomes that is essential for preventing crystal-induced kidney ...

Lysosomes, often reductively referred to as the "garbage disposals" of cells, play a pivotal role in our cells’ digestive systems by getting rid of unwanted materials. Now in a groundbreaking study, ...

A recent study published in EMBO Reports by researchers from Osaka University and Nara Medical University sheds light on a fundamental process within cells-microautophagy-that plays a crucial role in ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, No. 45 (November 5, 2019), pp. 22619-22623 (5 pages) Contacts between the endoplasmic reticulum (ER) and ...

Researchers at Duke-NUS Medical School and colleagues in Singapore have identified a protein that transports degraded membrane lipids out of lysosomes, cellular organelles that are the breakdown ...

This is a preview. Log in through your library . Abstract Peripheral nerves undergoing degeneration are favorable material for studying the types, origins, and functions of lysosomes. The following ...

In a rare disease called mucolipidosis type II, people's hearts and abdomens swell, and their bones grow malformed. In a rare disease called mucolipidosis type II, people's hearts and abdomens swell, ...