A joint effort involving research teams from Vanderbilt University Medical Center (VUMC) and the University of Michigan has linked the activities of a regulatory gene network and functional defects in ...

ZyVersa Therapeutics (ZVSA) highlights data from an article published in the peer-reviewed International Journal of Nanomedicine titled Small Intestinal Endocrine Cell Derived Exosomal ACE2 Protects ...

Type 2 diabetes (T2DM) is a systematic multi-organ metabolic disease, which is characterized by dynamic interplay among different organs. Pancreatic islet-liver axis is closely associated with normal ...

Researchers published the study covered in this summary on researchsquare.com as a preprint that has not yet been peer reviewed. Higher 25(OH)D levels associated with better homeostasis between ...

The currently approved islet-transplant method infuses islets into a vein in the liver. This invasive procedure requires the long-term use of immune-suppressing drugs to prevent islet rejection, ...

The main cause of all forms of diabetes is pancreatic beta-cell dysfunction. Beta cells, found in the pancreatic islets, store and release insulin. Decades of research with animal and cellular models ...

Long-term Western diet impairs islet blood vessel function and insulin transport even after diet reversal and weight loss, according to a new study from researchers at Karolinska Institutet. A new ...

Wenzhou Medical University researchers have reimagined the spleen as a viable site for islet transplantation, enabling long-term diabetes control without the burden of full immunosuppression.

In a recent study published in Nature Communications, researchers used a murine model to demonstrate that functional excision of murine phosphatidylinositol transfer protein alpha (PITPNA) impaired ...

Melton pioneered the differentiation of insulin-producing beta cells from human stem cells, giving Alvarez-Dominguez unparalleled training under one of the field’s founders. He also knew something ...