The lower hinge of immunoglobulin G (IgG), an overlooked part of the antibody, acts as a structural and functional control hub, according to a study by researchers at Science Tokyo. Deleting a single ...

Deleting a single amino acid (Pro230) in the lower hinge produced half-IgG1 molecules with disrupted disulfide bonds and reoriented Fab and Fc regions, highlighting the hinge’s essential role in ...

A Japanese research team has uncovered how sugar chains (glycans) modifications dynamically regulate the structure and function of human immunoglobulin G (IgG) antibodies. By integrating nuclear ...

A recent study published in Cell Reports demonstrated that vaccine-induced antibody functions against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diminish with age. Study: BNT162b2 ...

Breast milk is not just nutrition; it’s an immune delivery system, passing along cells, cytokines, and antibodies that protect the newborn and begin to train their immune system. Prior studies on ...

Rubella antibodies in the blood mean that a person’s immune system has developed a response to the rubella virus. A positive result for rubella immunoglobulin (IgG) antibodies means a person is immune ...

A collaboration led by UCLA and the Seattle Children’s Research Institute has yielded new knowledge about the genes responsible for the production and release of immunoglobulin G, the most common type ...