Add Yahoo as a preferred source to see more of our stories on Google. If you constantly feel hungry no matter how you try to manage your appetite, a hormonal imbalance known as leptin resistance could ...

Most obese patients grow resistant to satiety signals from the hormone leptin. A new study shows that leptin sensitivity can be restored in mice, leading to weight loss. Worldwide obesity rates have ...

Defects in POMC-expressing neurons are also known to cause leptin resistance and obesity, Friedman notes, adding, "it was satisfying to find that an acquired form of leptin resistance targets this ...