Treatments against hepatitis C virus have only been partially successful. A major problem is that antivirals generate drug resistance. Now Seong-Wook Lee of Dankook University, Yongin, Republic of ...

Hepatitis C virus (HCV) is a major cause of chronic liver disease worldwide. The severity of disease varies widely from mild illness to cirrhosis and hepatocellular carcinoma. The progression of liver ...

Nicola Fletcher, Jane McKeating and colleagues have demonstrated that human brain endothelial cells express all the main receptors required for HCV entry. “This is the first report that cells of the ...

A new compound that inhibits the replication of hepatitis C virus (HCV) in several stages of its lifecycle - and is also capable of acting on bacteria, fungi and cancer cells - has been synthesized by ...

The development of resistance to direct-acting antivirals (DAAs) targeting the hepatitis C virus (HCV) can compromise therapy. However, mechanisms that determine prevalence and frequency of resistance ...

This is a preview. Log in through your library . Abstract Triple antiretroviral therapy combining reverse transcriptase and protease inhibitors modifies the prognosis for human immunodeficiency virus ...

(A) Immunofluorescence staining of HCV-core protein in HCV replicating Huh7 cells. (B) FACS analysis of EpCAM and CD44 expression in HCV replicating Huh7 cells. (C) RTD-PCR analysis of HCV-RNAin ...

Small Molecule Combination Therapies Are Being Investigated to Increase Response Rates Researchers agree that now is a crucial time to be involved in hepatitis C virus (HCV) research. “Current ...

SARS-CoV-2 has infected over 71.5 million people and claimed over 1.6 million lives globally since December 2019. The mitigation strategies implemented worldwide have slowed down the pace of this ...

Hepatitis C is the leading cause of chronic liver disease and liver cancer in the world and affects an estimated 51 million people globally. Though the viral infection is easily diagnosable and ...

Occult HCV and HBV infections are recently identified entities whose existence became evident when nucleic acid amplification assays of enhanced sensitivity were employed for the detection of viral ...