The human genome contains about 23,000 genes, but only a fraction of those genes are turned on inside a cell at any given time. The complex network of regulatory elements that controls gene expression ...
A study published in the journal Cell marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells.
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Mapping 3D-super-enhancers with machine learning to pinpoint regulators of cell identity
Scientists usually study the molecular machinery that controls gene expression from the perspective of a linear, two-dimensional genome—even though DNA and its bound proteins function in three ...
The mammalian cortex, the region of the brain responsible for a wide range of higher-level cognitive functions, including sensory perception, motor control, and complex thought, is composed of a ...
A new class of AAVs has arrived. In six coordinated studies published on 21 May across Neuron, Cell, Cell Reports, and Cell Reports Methods, scientists unveil viral vectors fitted with ...
(L to R) Corresponding author Brian Abraham, PhD, and co-first authors Kelsey Maher, PhD, and co-first author Jie Lu, PhD, all of the St. Jude Department of Computational Biology. Cells express ...
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