ILT7 is selectively expressed on plasmacytoid dendritic cells, and daxdilimab binding is intended to reduce pDCs in tissue ...

EPFL researchers have successfully engineered cells of the immune system to more effectively recognize cancer cells. The work, covered in two papers, turns the previously lab-based method into a ...

For her Ph.D. at VUB and KULeuven, Aarushi Caro created a kind of systematics for dendritic cells, a special group of immune cells in the fight against cancer. Until now, there was a lot of confusion ...

Dendritic cells alter the chemokine gradient they follow to direct themselves to the lymph nodes. An immune response is an impressive feat of collective migration involving many cell types and ...

The immune system consists of inflammatory and regulatory T cells (Tregs) that promote or dampen immune activity, respectively. These cells react to specific antigens that specialized cells like ...

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) show that active mitochondria maintain dendritic cells, the immune system's sentinels, in a "ready-to-respond" ...

In a discovery that reframes how scientists understand one of the most common causes of nephrotic syndrome, researchers have shown that podocytes—the delicate filtration cells of the kidney—are not ...

In a new study published in Science titled, “Mitochondrial metabolism and signaling direct dendritic cell function in antitumor immunity,” researchers from St. Jude Children’s Research Hospital have ...

Researchers at LMU have discovered how a metabolite produced by gut bacteria can influence brain damage after stroke. Their ...