Every time a cell copies its DNA, parts of the genome are exposed and vulnerable to damage or errors. Molecular biologist ...

Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment ...

DNA replication in eukaryotic cells is a highly coordinated, multi-step process that ensures precise duplication of the genome prior to cell division. In late mitosis and early G1 phase, the Origin ...

If you are anything like us, whenever you plan a journey, you spend a remarkable amount of time thinking about the start and ...

Researchers at the University of Minnesota have developed what they describe as the world’s ...

Tiny, quivering spheres designed to feed and multiply raise prospect of artificial organisms to make drugs, food and fuel ...

For almost 60 years, scientists have tried to understand why DNA doesn’t replicate wildly and uncontrollably every time a cell divides – which they need to do constantly. Without this process, we ...

A representative figure showing that HELQ-deficient cells fail to undergo normal fork slowing after MMC (a crosslinking agent) treatment, consistent with defective fork reversal. Every time a cell ...

The cells' attempt to restart the stalled replication fork subsequently prompted the formation of single-strand DNA breaks that necessitated repair with another protein known as poly (ADP-ribose) ...

DNA replication is the process by which a cell makes an identical copy of its DNA. This process is performed at the beginning of every cell division so that when the cell divides, each daughter cell ...

Scientists have discovered that a gene normally considered a DNA-protecting "good guy" can become dangerous when cells make too much of it. The gene, EXO1, acts like molecular scissors that help ...