In one of the many exciting matchups on the NFL slate in Week 5, the San Francisco 49ers and the Los Angeles Rams take the field at SoFi Stadium.

The Browns take a 21-game regular-season losing streak in Pittsburgh into the game against the Steelers.

Quarterback Joe Flacco will start for the Bengals and if Cincinnati wins he'd be the only quarterback in the Super Bowl era to beat the same team twice in a season playing for different teams – Flacc...