Physicists introduce phase contrast to electron microscopy, delivering sharper images of our body's tiniest proteins

Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which ...
The Scientist

Improvements In Light Microscopy Lead To New Applications

The invention that first enabled researchers to see clear images of living cells was the phase-contrast microscope, which won its inventor, Frits Zernike, a Nobel Prize in 1932. Prior to Zernike's ...
Nature

Quantitative phase imaging by gradient retardance optical microscopy

Quantitative phase imaging (QPI) has become a vital tool in bioimaging, offering precise measurements of wavefront distortion and, thus, of key cellular metabolism metrics, such as dry mass and ...
Nature

Machine learning approach for recognition and morphological analysis of isolated astrocytes in phase contrast microscopy

Astrocytes are glycolytically active cells in the central nervous system playing a crucial role in various brain processes from homeostasis to neurotransmission. Astrocytes possess a complex branched ...
insider.si.edu

Phase Contrast Microscope Objective Lens

IIIF provides researchers rich metadata and media viewing options for comparison of works across cultural heritage collections. Visit the IIIF page to learn more. Fritz Zernike (1888-1966), a Dutch ...