In a previous article, I made the case that little has changed within the antipsychotic drug landscape over the past 70 years since the only effective medications for the treatment of schizophrenia ...
SAN FRANCISCO — The US Food and Drug Administration (FDA) has granted breakthrough therapy designation to a potentially first-in-class psychotropic agent with a completely different mechanism of ...
Karuna Therapeutics focuses on developing therapies that target muscarinic cholinergic receptors to treat psychosis and cognitive impairment in CNS disorders. The Company's lead asset, KarXT, has ...
ENIGMA-TRS 2 is a global, randomized, double-blind, placebo-controlled 12-week Phase III clinical study designed to enroll at least 400 patients; topline results are expected by Q4 2026Evenamide is a ...
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Haloperidol is an antipsychotic drug commonly used to treat a range of neurological disorders, including schizophrenia, Tourette syndrome, bipolar disorder and others. The drug works by blocking ...
The question of putative mechanisms of action continues to haunt psychopharmacology. Put simply, we know these drugs work, but we have very little idea how. We make guesses based on the neurochemical ...
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