Full-body defense does not always look the way textbooks say it should. In planarian flatworms, a newly identified cell type ...

While intestinal stem cells (ISC) are essential for epithelial homeostasis, their dynamic regulation during immune-mediated injury remains undefined. Here we show that suppression of jejunal ISC ...

We discuss the components of the innate immune system, including natural killer (NK) cells, macrophages and neutrophils, as well as components of the adaptive immune system, including CD4 + and CD8 + ...

Autoimmune and autoinflammatory diseases have traditionally been interpreted as disorders arising from dysregulation of adaptive or innate immune responses, ...