Purpose: The efficacy and tolerability of quetiapine in the treatment of acute mania were reviewed. Summary: Five randomized, placebo-controlled trials involving quetiapine as monotherapy or adjunct ...
Background The major diagnostic classifications consider mania as a uni-dimensional illness. Factor analytic studies of acute mania are fewer compared to schizophrenia and depression. Evidence from ...
4M Therapeutics Inc. has announced the presentation of preclinical data on its small-molecule glycogen synthase kinase-3β (GSK-3β) inhibitors in models of bipolar disorder.
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