A simulation study couples a chaotic three-dimensional tumor growth model with an advanced filtering technique to estimate ...
A platinum(IV) prodrug covalently attached to mesoporous silica nanoparticles showed significantly greater cytotoxicity than ...
Research and drug discovery are undergoing a transformation, driven by the rise of 3D cell culture models that better replicate human biology. Unlike traditional 2D cultures and animal models, which ...
Two cancer drugs appeared almost identical in conventional screening, but a new 3D Cell Painting method exposed striking ...
Researchers at Uppsala University have adapted Cell Painting, a widely used imaging method in drug discovery, to look at ...
For decades, the default place to study human cells has been a flat sheet of plastic. Cells grown on two-dimensional (2D) surfaces are easy to handle and easy to image, and that convenience is real.
Newswise — Most cells in the human body exist in complex three-dimensional environments, yet they are still commonly studied on flat plastic dishes. These two-dimensional cultures distort cell ...
Led by the NORLUX Neuro-Oncology Laboratory at the LIH Department of Cancer Research, the team developed an advanced co-culture system combining patient-derived glioblastoma organoids with human T ...
Post-thaw assessment can evaluate survival, model integrity, recovery, and cell function after cryopreservation.
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