Michigan cornerback Will Johnson is not expected to play against Ohio State on Saturday, leaving the Wolverines without their top defensive back and the program's highest-regarded NFL draft prospect.

Michigan Wolverines All-American cornerback Will Johnson is set to miss Saturday's annual rivalry game against the No. 2 Ohio State Buckeyes with his nagging toe injury, according to a report from Matt Zenitz of CBS Sports.

Michigan is expected to be without star cornerback Will Johnson vs. Ohio State, a source tells @CBSSports / @247Sports. Sherrone Moore had said “we’ll see” earlier in the week re: Johnson, who has been out since early October due to a toe injury. https://t.co/ly2NQ7Y5mp pic.twitter.com/y2hUQ9VNTB

The Wolverines enter the annual rivalry showdown as nearly three-touchdown underdogs, setting the stage for what could be a lopsided affair at Ohio Stadium (Noon, FOX). Earlier this week, head coach Sherrone Moore left the door open for tight end Colston Loveland and cornerback Will Johnson to play.

ANN ARBOR, Mich. — Michigan coach Sherrone Moore wants to hear from the doctors, but apparently, they’ve already spoken. Cornerback Will Johnson has missed the last four games with a toe injury, and Moore said Monday that Michigan will know later this week whether Johnson can play Saturday against Ohio State.

Yeah. I just go by what the doctors say,” Michigan coach Sherrone Moore said on Will Johnson injury status and Colston Loveland ahead of Ohio State.

Michigan is currently three-touchdown underdogs heading into Columbus to take on Ohio State on Saturday. The Wolverines have won three in a row over Ohio State,

Michigan cornerback Will Johnson, the star of the Wolverines’ secondary, is not expected to play against Ohio State on Saturday, according to multiple reports.