San Francisco 49ers head coach Kyle Shanahan said he had big comebacks in mind when he kept Christian McCaffrey on the field with his team leading by 19 late in Sunday's game.

The San Francisco 49ers notched a fairly impressive, and expected, win against the Arizona Cardinals. It was a nice rebound after getting throttled last week. P

Former Pro Bowl RB LeSean McCoy believes the Arizona Cardinals point shaved in their Week 11 loss to the San Francisco 49ers.

Five weeks after the San Francisco 49ers expected to have star wide receiver Brandon Aiyuk back from injury, the All-Pro wideout still has yet to be activated from the physically unable to perform list.

The 49ers drafted Martin to play their WILL spot, which is the weakside linebacker spot. This is the position Dee Winters plays, not Warner and Bethune. Warner played the MIKE, which is in the middle, and gets the defense aligned. The WILL is more about run-and-chase. They are asked to do different things.

Ever since training camp last year, the San Francisco 49ers have been hit with one injury to a key player after another. They haven't gotten any type of respite from the injury bug, and it resulted in them going 6-11 and missing the playoffs last season after coming off a narrow loss in Super Bowl LVIII.

The 49ers head to State Farm Stadium to face the Arizona Cardinals with Brock Purdy back under center. Purdy was cleared off the injury report and is starting after missing six games with a turf-toe variant.

QB Brock Purdy connected with TE George Kittle for two touchdowns on the day, marking the 23rd touchdown pass that Purdy has thrown to Kittle. The duo's 23 touchdowns are the second-most by a 49ers QB/TE duo in franchise history.