A disastrous fifth inning doomed the Giants in San Francisco's 8-4 loss to the San Diego Padres on Thursday afternoon at Petco Park.

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Manny Machado drove in three runs against Justin Verlander and the San Diego Padres beat the San Francisco Giants 8-4 in a sloppy game.

Manny Machado drove in three runs against Justin Verlander and the San Diego Padres beat the San Francisco Giants 8-4 on Thursday in a sloppy game. The Padres took three of four from the Giants and have won three straight going into a second straight weekend showdown against the defending World Series champion Los Angeles Dodgers.

The Padres tied a game they shouldn’t have trailed in the fourth inning, scored six runs in the fifth inning with help from a two-error play and survived a burst of a comeback powered by back-to-back homers off Dylan Cease at the start of the sixth.

The San Diego Padres (71-56) and San Francisco Giants (61-66) will meet on Thursday at PETCO Park, with first pitch at 4:10 p.m. ET. The Padres are the home favorite (-139) versus the Giants (+118). The Padres will start Dylan Cease (5-11) against the Giants and Justin Verlander (1-9).