A gunman killed UnitedHealthcare’s CEO on Wednesday in a “brazen, targeted attack” outside a Manhattan hotel where the health insurer was holding its investor conference, police said, setting off a massive search for the fleeing assailant hours before the annual Rockefeller Center Christmas tree lighting nearby.

A manhunt is underway in Manhattan after the CEO of UnitedHealthcare was shot Wednesday morning, according to the New York Police Department. Brian Thompson, 50, was shot near the New York Hilton on Sixth Avenue just before 7 a.m.

The CEO of UnitedHealthcare has been fatally shot in New York City in what appeared to be a targeted attack, according to reports. The New York Post was the first to report Brian Thompson, 50, was shot outside the Hilton hotel in Manhattan’s Midtown at around 6:46 a.m. on Wednesday. Bloomberg also named Thompson as the victim of a shooting.