San Francisco 49ers tight end George Kittle (85) celebrates his touchdown catch with teammates Jake Tonges (88) and Kendrick Bourne (84) during their game against the Arizona Cardinals at State Farm Stadium in Glendale on Nov. 16, 2025. / Joe Rondone/The Republic / USA TODAY NETWORK via Imagn Images

Arizona Cardinals head coach Jonathan Gannon is ignoring the hot seat rumors after Sunday's humiliating 41-22 loss to the San Francisco 49ers.

SANTA CLARA, Calif. (AP) — Brock Purdy returned to the lineup and the San Francisco 49ers scored their most points in nearly two years. While Purdy looked sharp in the 41-22 victory over the Arizona Cardinals on Sunday, the reasons behind the big scoring output have to do with a lot more than just the change at quarterback.

This article was originally published on www.si.com/nfl/49ers/onsi as Three 49ers Whose Stock Increased in the Win Against the Cardinals. The San Francisco 49ers notched a fairly impressive, and expected, win against the Arizona Cardinals.

Wilson caught 15 passes for 185 yards, coming close to matching in one game his entire season's production previously.

The 49ers' team captains stepped up in Arizona. One of them, George Kittle, said the team is positioned right where it needs to be.

A big stretch of games begins for the San Francisco 49ers on Sunday in Arizona against the Cardinals. Here's how to watch their Week 11 showdown.

Preview the Week 11 matchup between the San Francisco 49ers and Arizona Cardinals with predictions, odds, over/under, spread, betting lines and more.

The 49ers have their franchise quarterback back. "He was vintage Brock," Christian McCaffrey said. "That's a huge compliment."